Are Biopsies Painful?

Todd W Franzen

March 12, 2019

There is no good way to say that a Biopsy is a simple procedure or an event that will not cause you any discomfort. Are Biopsies Painful? Unfortunately, Yes they are.

It’s been important for me as a survivor to start being involved. Many people are really confused and scared about the process that goes on after you’ve been diagnosed or as you are being diagnosed.

Many things go on when you start down this road. And there’s a lot of fear that goes on because you are jumping into the unknown. The good news is you might start getting some answers to what is going on with you. Why you might be feeling as bad as you have.

I want to share a little bit of my story about the first couple of days within my diagnosis.

The intention that it’ll help give you an idea of what to expect.

When I went into the hospital, I went in because I had what felt like gas pains. I had a cramp in my right side underneath my rib cage, right around where my liver sits. The pain came on very unexpectedly on a sunny day in November. As the day went on, it didn’t get any better and things transpired from there.

The Next Step

I told myself if it doesn’t get any better by the next day, I’m going to go to the hospital emergency room. And that’s what ended up happening the next morning. I woke up, and moved around, that cramp came right back.

Mom drove me down to the emergency room the following morning. That’s where my story really started to unfold. I did a CT scan of my chest area and we were able to determine that the scan of my liver did not look right. And it actually looked like a bag of birdseed. That is what the consistency looked like. Just really kind of spotty. There was no solid consistency to it.

So we end up getting me down to Saint Anthony’s Central Hospital in Denver that night.


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That’s where everything started to get real.

Within the first three days, I had a liver biopsy, and a lymph node surgically removed under my armpit. And by day five, the pathology came back saying I was diagnosed with Hodgkin’s Lymphoma. Are biopsies painful? Yes they are!

My First PET Scan and Chemo

This is when I underwent my first pet scan and that was just absolutely crazy. And By day 10, my first round of chemotherapy. And that’s where my world of reality became absolute mayhem.

Over time, it got a little bit easier for me to process. I started to understand the routine and was able to move forward and learned to zone everything out. But was still dealing with a lot of fear from my own mortality. And I didn’t know how to deal with that stress. I talked to counselors about what I was going through. Fortunately, there were some resources at hand to help me deal with that. So that was one of the biggest things.

I want to really focus back on the biopsy side of my experience. Some of the questions that I’ve been answering are on Reddit and Facebook about biopsies and if they’re painful. I vividly remember the needle going into my side right below my lower right rib.

“The liver biopsy felt like I was being stabbed, slowly”. – Todd Franzen

The surgeon taking pieces of my liver. I could feel him just in there. It was the weirdest, painful thing I’ve ever felt in my life. I could feel a little grabber is coming in and, and just grabbing and tearing pieces. The surgeon took six little pieces of my liver. Immediately after the sixth biopsy was taken, they knocked me out.

It took a little bit of mental preparation for me. Fortunately, I had a friend that had gone through a liver biopsy due to a different disease. He informed me about it and that it’s going to suck, but there’s just no way around it.

Always a mental challenge

So prepare yourself mentally to have the biopsies done.

Once I had a recurrence, I had another biopsy done. At a different place in my body.

We tried to do a bronchoscopy at first. THat biopsy is where you go through the nose. We tried to get a lymph node sample that was essentially right above my heart in my chest. The best way the doctor wanted to go was through my nose to see if they could get it. But because it’s in such a precarious place, they couldn’t do it.

The next procedure was called a mediastinoscopy.

They ended up opening me up in my neck where a tracheotomy would be. We were able to get a biopsy of that lymph node and confirm that my Hodgkin’s came back. Fortunately, I was knocked out for this biopsy because of the incision in my neck.

And that’s where everything kind of led down the road to my autologous stem cell transplant.

With the Liver biopsy, because the liver metabolizes drugs so quickly, that is the main reason why they didn’t knock you out. And I just had to endure the pain of it. It taught me that this is something that you deal with when you’re going through cancer.

Shit Happens!

Everything that could happen, can happen. It doesn’t mean it will, but it’s good to shift that focus, mentality, and that mindset into.

I got to do what I gotta do to make sure that I can get through this as quickly and as health-wise as I possibly can.

So just remember, you’re going through a diagnosis and if you have to do biopsies, just mentally prepare yourself that it’s going to suck. And if you can your mindset that way, it’s going to make the entire experience a little bit better.

You will start to feel a little more comfortable knowing that you can move on to the next challenge once you do this.

I’ve always been kind of one to just jump in and take action to get this thing done. I want to do this now. I want to get it over with. So if I can do that and if I can make that happen as fast as possible, then so be it.

And that’s how I approached my liver biopsy.

And the rest of it for me is history. Take the time to really prepare yourself for biopsy because there’s undoubtedly a lot of fear that goes on and a lot of confusion and anger.

And I mean you will go through the entire gamut of feelings, not only because you’re going through cancer, but now you have to do all these surgical procedures that really keep you on your toes. And if you can, prepare yourself for all the anxiety that comes up and when you’re first starting, understand there is no easy way to approach cancer.

It’s not easy. None of it’s easy!

A lot of positive self-talk, a lot of meditation, a lot of doing your best to be around people that can support you as best as you can. And I know that there are a lot of you out there that don’t have the support.

So this is where you have to dig really deep and be your own best support group. Fortunately there starting to be some more survivor and patient resources online starting to pop up, which is really good. Facebook has a couple of good ones, Reddit has some really good ones too. Also, Quora is a good place to ask questions.

So please take a look at those and ask your questions because there are plenty of people that have been out there.

Unfortunately, the medical industry has not done a very good job of helping with survivorship issues, psychological problems, and other physical problems. You kind of must go at it alone, but I want you to know that you’re not alone.

Be prepared, start doing a little bit of research. You’re going to be okay and you’re just gonna fight as you’ve never fought before.

Thanks for reading and If you have any questions, hit me in the comment section below.

Todd

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Todd W Franzen


I am a two-time Hodgkin's lymphoma survivor with 17 years of documented cancer survivorship experience that spans multiple treatment eras. My journey began in November 2009 with a Stage 4B diagnosis at age 33, and continued through recurrence and treatment in 2019-2021. This rare longitudinal perspective—living through two complete treatment cycles a decade apart—gives me comparative insight into cancer care evolution that no single medical professional can replicate.

MY TREATMENT EXPERIENCE

First Treatment Cycle (2009-2010)
• 12 infusions of ABVD Chemotherapy over 6 months
• 2 infusions of ICE Chemotherapy (4-day infusions)
• 1 infusion of BEAM Chemotherapy
• 1 Autologous Stem-Cell Transplant
• 8 PET Scans
• 6 CT Scans

Second Treatment Cycle (2019-2021)
• 2 infusions of Brentuximab and Bendamustine
(Severe allergic reaction to Brentuximab — hives)
• 25 rounds of Radiation to Mediastinum (46RAD combined)
• 4 infusions of Keytruda Immunotherapy
• 2 infusions of IGEV Chemotherapy (5-day infusions)
• 1 Total Body Radiation (2RAD)
• 1 Sibling Allogeneic Stem-Cell Transplant
• 6 PET Scans
• 6 CT Scans

COMPARATIVE EXPERTISE

Surviving two stem-cell transplants—one autologous, one sibling allogeneic—across different decades of cancer treatment has given me firsthand experience with nearly every major modality in lymphoma care: combination chemotherapy, salvage chemotherapy, immunotherapy, radiation protocols, and both types of stem-cell transplantation. I've experienced treatment side effects from the "standard" ABVD era through the modern immunotherapy period.

This comparative expertise matters for survivors. Treatment protocols in 2009 looked very different from 2019, and the long-term survivorship implications are still emerging. Doctors treat; survivors live with the aftermath. I've done both—twice.

CREDENTIALS & PROJECTS

• Founder: Strap In For Life 501(c)(3) nonprofit
• Author: Internal Architect: A Cancer Survivor's Memoir
• Licensed Insurance Agent (practical healthcare system navigation)
• 17-year cancer survivor documenting the journey since 2008

WHAT I WRITE ABOUT

Cancer survivorship doesn't end when treatment stops—it's when the real reconstruction begins. My blog covers:
• Practical survivorship (relationships, careers, identity)
• Treatment experience insights (what they don't tell you)
• Long-term effects and secondary health considerations
• Mental health and emotional reconstruction
• Healthcare system navigation

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